Article Published In Vol. 05, Issue 01 (2025)

CHARACTERIZATION AND DEGRADATION OF ANTIBIOTIC CEFADROXIL BY SELECTED BACTERIAL ISOLATES

Author : Virendra Kumar and Archana Shrivastav

Abstract

Aim: Antibiotic contamination in the environment is a growing concern, especially with commonly used drugs like Cefadroxil. This study aimed to isolate and characterize bacterial strains capable of degrading Cefadroxil under optimized laboratory conditions.

Method: Soil samples were collected from different locations, and bacterial isolates were enriched and screened for their ability to tolerate and degrade Cefadroxil at various concentrations.

Results: Among the isolates, CFR-10 showed the highest degradation efficiency, achieving 50% degradation after 72 hours. Morphological, biochemical, and molecular studies confirmed CFR-10 as closely related to Enterobacter cloacae. The bacterial isolates also demonstrated resistance to several heavy metals, indicating their ability to survive under stressful conditions.

Conclusion: This study highlights the potential use of indigenous bacterial strains for the bioremediation of Cefadroxil-contaminated environments.

Keywords: Cefadroxil degradation, Bioremediation, Enterobacter cloacae, Antibiotic pollution, Heavy metal resistance, Indigenous bacteria